Background: Hydronephrosis is a relatively common condition in which an anatomic or functional problem causes obstruction to normal urinary flow. Urinary tract infections which is combined with hydronephrosis, also called secondary urinary tract infections, are more complicated and poor outcomes than primary urinary tract infections. In this study, we investigate the patients with urinary tract infection in one university hospital, with the ratio of hydronephrosis, the clinical and microbiological differences and its prognosis.
Methods: In the period from Jan.2008 to Dec.2010, all patients urinary tract infections who were diagnosed with hydronephrosis in CT findings were enrolled. We reviewed medical records retrospectively about the ratio of hydronephrosis, difference between the clinical, microbiological features and prognosis of uncomplicated pyelonephritis and hydronephrosis.
Results: Of the 505 patients were diagnosed with UTI by abdominal CT during the study peroid, only 52 patients with UTI with hydronephrosis were diagnosed. The most common cause of UTI with hydronephrosis is ureter stone and kidney stone, the 2nd is neurogenic bladder. In case of UTI with hydronephrosis, variable bacterias can be the causative one, still the most common pathogen is E.coli (33%). In case of UTI with hydronephrosis, the attack rate of azotemia is higher, and clinical severity may be higher than UTI.
Conclusions: In UTI with hydronephrosis, the most common cause is ureter stone and kidney stone and the most common pathogen is E.coli. In case of UTI with hydronephrosis, clinical severity may be higher than uncomplicated UTI.